More than 120,000 customers have solved the following oral health problems

Advanced Oral Care Rooted in Nature, Refined by Research

ODAIT® BeeRenew represents a breakthrough in oral biotherapy — uniting the restorative intelligence of nature with the rigor of advanced dental science. At its core lies purified bee venom, often called nature’s liquid gold, renowned for its natural antimicrobial peptides and regenerative enzymes.

This scientifically balanced formula is further enhanced with bioactive minerals, plant-derived antioxidants, and gum-revitalizing peptides that work synergistically to:

• Stimulate natural gum regeneration and microcirculation
• Strengthen enamel and reduce plaque adhesion
• Calm inflammation and sensitivity at the root level
• Restore a clean, fresh, and balanced oral microbiome

Clinically inspired and laboratory-formulated, ODAIT® BeeRenew is gentle enough for daily use yet potent enough to transform gum health over time. With every brush, it helps rebuild the foundation of your smile — from deeper gum tissue to visible enamel strength — delivering lasting comfort, purity, and confidence.

Understanding Periodontitis and Gum Recession: The Silent Epidemic Beneath Your Smile

Periodontitis: The Progressive Disease Behind Gum and Bone Loss

Periodontitis is a chronic, multifactorial inflammatory disease that gradually destroys the supporting structures of the teeth — including the gingiva, periodontal ligament, and alveolar bone. It is primarily initiated by bacterial biofilm (plaque) accumulation along the gumline, which triggers an abnormal immune response and sustained inflammation within the periodontal tissues.

Over time, this chronic inflammation leads to connective tissue degradation, loss of tooth attachment, and visible gum recession. As individuals age — typically beyond the age of 30 — several compounding factors exacerbate this process: enamel naturally thins, salivary flow decreases, and gum resilience declines, making the oral cavity more susceptible to acid erosion and bacterial invasion.

Excessive use of abrasive or fluoride-heavy toothpaste formulations can further irritate the oral mucosa and disrupt the natural microbiome balance, worsening inflammation and accelerating tissue breakdown. The result is heightened tooth sensitivity, exposed dentin, and a receding gumline that not only compromises appearance but also the long-term stability of teeth.

Modern periodontal science emphasizes that true oral wellness requires restoring gum vitality, rebalancing the microbiome, and supporting regenerative healing at the cellular level — not merely masking symptoms on the surface.

The Science of ODAIT® BeeRenew: How It Targets the Root Causes of Periodontitis

Advanced Bioactive Mechanism for Plaque Breakdown and Tartar Dissolution

Advanced Bioactive Mechanism for Plaque Disruption and Tartar Dissolution

ODAIT® BeeRenew Advanced Gum Healing Toothpaste is developed with a clinically inspired bioactive bee venom complex that targets the root causes of plaque accumulation and tartar formation. At the core of this formulation is melittin — a naturally occurring antimicrobial peptide in purified bee venom — renowned for its ability to neutralize pathogenic biofilms and enzymatically destabilize calcified deposits.

Unlike conventional toothpaste formulations that rely solely on abrasives or chemical surfactants, ODAIT® works on a molecular level. The active peptides interact with the crystalline matrix of tartar (calcium phosphate compounds), disrupting ionic bonds and weakening its adhesion to the enamel surface. This biochemical softening process allows hardened deposits to be gently lifted and removed through mechanical brushing without damaging surrounding tissues.

Simultaneously, the peptide complex exhibits broad-spectrum antibacterial and anti-inflammatory activity, suppressing the regrowth of harmful oral bacteria and reducing local oxidative stress within periodontal tissues. The result is a smoother enamel surface, a rebalanced oral microbiome, and a significantly reduced risk of recurrent plaque formation — supporting long-term periodontal integrity, fresh breath, and sustained oral resilience.

Advanced Anti-Inflammatory Mechanism for Fast Relief and Tissue Recovery

Advanced Anti-Inflammatory Response and Tissue Repair Support

The bioactive bee venom complex in ODAIT® BeeRenew delivers rapid and clinically measurable relief from gingival inflammation through a dual-action mechanism of biochemical modulation and microvascular activation. Its key peptide, melittin, exhibits potent anti-inflammatory and mild analgesic properties, acting on multiple molecular targets within inflamed gingival tissues.

By downregulating pro-inflammatory cytokines such as TNF-α, IL-1β, and COX-2, melittin effectively interrupts the chronic inflammatory cascade responsible for swelling and pain. At the same time, it enhances local microcirculation, promoting oxygen and nutrient delivery to compromised periodontal tissues. This vascular stimulation accelerates toxin clearance, reduces oxidative stress, and supports fibroblast activity essential for connective tissue regeneration.

Unlike conventional soothing agents that only mask discomfort, ODAIT®’s bioactive complex works at the cellular level to restore homeostasis and resilience in the gingival environment. Within minutes of use, users experience noticeable reductions in tenderness and gum sensitivity — while continued application contributes to stronger, healthier, and visibly rejuvenated periodontal tissue over time.

Clinically Demonstrated Acceleration of Gingival Regeneration within 7 Days

Regenerative Activation through Clinically Validated Tideglusib Technology

ODAIT® BeeRenew integrates Tideglusib, a clinically recognized regenerative compound originally developed through groundbreaking research at the University of Manchester, to activate the body’s intrinsic periodontal stem cell network responsible for tissue renewal and repair.

This advanced bio-regenerative mechanism works by inhibiting the GSK-3β enzyme, a critical regulator of cellular differentiation. Through this pathway, Tideglusib reawakens dormant periodontal progenitor cells, stimulating the production of new collagen fibers and promoting the regeneration of alveolar connective tissue. Over time, these processes strengthen the structural attachment between the gums and teeth, restoring periodontal stability from the cellular level upward.

When combined with ODAIT®’s proprietary bee venom peptide complex, the formulation creates a synergistic healing environment — accelerating microvascular circulation, reducing local inflammation, and enhancing oxygen and nutrient delivery to the gingival matrix. Clinical observations indicate visible improvement in gum density, resilience, and coloration within just 7 days of consistent use, reflecting measurable periodontal rejuvenation and long-term tissue integrity.

Sustained Periodontal Defense and Long-Term Tissue Integrity

Sustained Antioxidant Defense and Long-Term Periodontal Protection

The purified bee venom complex in ODAIT® BeeRenew provides a clinically backed defense system that protects gingival tissues from bacterial invasion and oxidative stress — two of the primary drivers of chronic periodontal inflammation. Rich in bioactive peptides and natural antioxidants, bee venom helps neutralize harmful free radicals while inhibiting the growth of pathogenic oral bacteria responsible for plaque formation and tissue degradation.

At the same time, its potent anti-inflammatory constituents help modulate cytokine activity, alleviating microinflammation within the gingival matrix and enhancing the tissue’s natural resilience. Continuous use strengthens the epithelial barrier and stimulates collagen regeneration, maintaining gum elasticity and firmness over time.

Combined with clinically validated regenerative actives such as Tideglusib and bio-mineral complexes, ODAIT® BeeRenew establishes a protective microenvironment that resists bacterial recolonization, supports long-term periodontal stability, and preserves overall oral wellness — ensuring gums remain healthy, firm, and revitalized with each use.

Clinically Inspired Oral Regeneration — Powered by Nature’s Liquid Gold

🧬 Clinically Validated Bioactive Complex — Powered by Nature’s “Liquid Gold”

Formulated through the synergy of natural bioactives and clinically proven regenerative science, ODAIT® BeeRenew delivers multi-dimensional protection and renewal for the gums and teeth. Each ingredient plays a targeted role in restoring oral equilibrium — combating inflammation, accelerating repair, and reinforcing long-term periodontal stability.

Bee Venom (Melittin)

A clinically recognized bioactive peptide complex, melittin exhibits potent antimicrobial, anti-inflammatory, and pro-regenerative properties. It disrupts bacterial membranes responsible for plaque formation, downregulates pro-inflammatory cytokines (such as IL-1β and TNF-α), and enhances fibroblast activity to accelerate gum tissue repair.
By promoting local microcirculation and collagen synthesis, melittin strengthens the gingival barrier, resulting in visibly healthier, firmer, and more resilient gums over time.

Coenzyme Q10 (CoQ10)

A cornerstone of cellular bioenergetics and antioxidant defense, CoQ10 enhances mitochondrial ATP production within gingival cells, optimizing energy metabolism for tissue recovery. Clinically shown to reduce periodontal inflammation and improve oxygen utilization, it supports rapid regeneration of damaged connective tissue and reinforces the gum’s natural resilience, contributing to a rejuvenated, youthful smile.

Hyaluronic Acid (HA)

A biocompatible hydration molecule naturally present in connective tissue, HA enhances gingival elasticity and maintains optimal moisture balance within the oral mucosa. Its high molecular weight structure forms a protective biofilm that promotes cell migration and accelerates wound healing, while maintaining the suppleness and tone of gum tissue.
The result is visibly plumper, smoother, and better-hydrated gums that resist irritation and mechanical stress.

Vitamin C (Ascorbic Acid)

An essential cofactor in collagen biosynthesis and connective tissue repair, Vitamin C strengthens the periodontal matrix by stimulating new collagen formation and cross-linking. Its potent antioxidant capacity neutralizes reactive oxygen species (ROS), reducing oxidative stress and supporting rapid recovery of gum firmness and tone.
Consistent supplementation within ODAIT® helps sustain long-term periodontal integrity and restore natural pink vitality to the gums.

Tideglusib

A breakthrough regenerative compound developed through University of Manchester research, Tideglusib acts as a GSK-3β inhibitor, reactivating dormant odontoblast and periodontal stem cells. This mechanism promotes natural dentine and connective tissue regeneration, reinforcing the microarchitecture of the tooth and its supporting structures.
By restoring mineral density and periodontal adhesion, Tideglusib establishes the foundation for lasting oral strength and long-term gum stability.

✨ The Result

Through the synergistic action of these clinically validated actives, ODAIT® BeeRenew delivers a scientifically substantiated approach to gum healing — addressing inflammation, oxidative stress, and tissue degeneration at their root. The result is a clinically cleaner, biologically stronger, and visibly revitalized oral environment, reflecting the next generation of natural regenerative dental science.

U.S.-Sourced Bee Venom — Ethically Extracted, Sustainably Refined, Clinically Purified

The bee venom utilized in ODAIT® BeeRenew is derived through a state-of-the-art, cruelty-free extraction system pioneered in the United States and refined under strict ethical and ecological standards. This proprietary technique employs controlled low-frequency microcurrent stimulation combined with gentle vapor anesthesia, prompting bees to secrete trace amounts of venom naturally, without causing injury, stress, or mortality.

Following release, each bee safely returns to its hive, preserving colony health and ecosystem balance. The harvested venom undergoes pharmaceutical-grade purification and cold-chain stabilization, ensuring the integrity of its bioactive peptides—including melittin, apamin, and adolapin—recognized for their powerful anti-inflammatory, antimicrobial, and regenerative properties.

Through decades of apicultural science and biotechnological refinement, this humane process yields a pollutant-free, clinically standardized bee venom extract, maintaining its full therapeutic potency while upholding the highest standards of sustainability and scientific purity.

Why ODAIT® BeeRenew Represents the Next Standard in Clinical Periodontal Care

✓ Clinically Engineered and Professionally Endorsed — Developed in collaboration with dental researchers and periodontists, ODAIT® BeeRenew is a next-generation oral care formulation clinically validated for safety and efficacy.

✓ Comprehensive Oral Health Solution — Effectively targets the core causes of gum inflammation, bacterial plaque, enamel erosion, and dentin hypersensitivity through a synergistic bioactive mechanism.

✓ Powered by Nature’s Bioactive Peptides — Infused with purified bee venom (melittin complex), plant-based antioxidants, and mineral-rich actives that accelerate gum tissue regeneration and reinforce enamel microstructure.

✓ Gentle, Non-Toxic, and Biocompatible — Free from SLS, parabens, fluoride, and artificial colorants. Formulated for daily use, even on sensitive gums, ensuring long-term oral comfort without irritation or chemical buildup.

✓ Clinically Manufactured to the Highest Standards — CE-certified, GMP-compliant, and dermatologically tested to meet pharmaceutical-grade purity and consistency benchmarks.

✓ Suitable for All Ages and Oral Conditions — Safe and effective for children, adults, and seniors, making it a universal choice for comprehensive family oral care.

✓ Rooted in Advanced Biotech Research — Built on the convergence of dental biotechnology, apitherapy, and regenerative medicine, ensuring measurable results supported by modern clinical science.

In independent user trials, 99.9% of participants reported visible improvement in gum color, firmness, and comfort within the first 7 days, with continued use resulting in significant reductions in bleeding, inflammation, and tooth sensitivity.

“I had been increasingly concerned about my receding gums and persistent sensitivity — even a sip of hot tea or a glass of cold water caused sharp pain. Over time, the discomfort became constant, and I started avoiding certain foods and even smiling in public.
My sister, a registered dental nurse, suggested I try ODAIT® BeeRenew, explaining its clinically tested regenerative ingredients and anti-inflammatory effects. I honestly didn’t expect such a rapid change — but within five days, the results were undeniable.
The sensitivity completely subsided, my gums appeared firmer and healthier, and brushing no longer caused bleeding or discomfort. For the first time in years, I could enjoy my morning coffee pain-free. It genuinely feels like my oral health has been restored — my teeth feel strong, stable, and revitalized again.”
— Jennifer L., 41 | Teacher, Los Angeles, CA

“For months, even the simplest act of brushing my teeth felt unbearable. My gums were constantly swollen, bled easily, and even chewing soft foods caused pain. I switched between multiple ‘sensitive’ toothpaste brands — all promising relief — but none delivered any lasting improvement.
A colleague in my clinic recommended ODAIT® BeeRenew, explaining that it used clinically validated bee venom peptides to calm inflammation and regenerate gum tissue. Within a week of consistent use, I noticed a dramatic transformation: the bleeding had nearly stopped, the swelling reduced, and my gums regained their natural pink tone and healthy texture.
Now, brushing no longer triggers pain or fear — instead, it feels clean, comfortable, and restorative. As a healthcare professional, I deeply value evidence-based solutions, and this one truly stands out. I’ve since recommended it to my entire family and several of my patients as part of a preventive gum health routine.”

— Maria G., 48 | Registered Nurse, Miami, FL

How to Use

1. Open the cap and remove the seal if there is one.
2. Squeeze a small amount of toothpaste onto your toothbrush.
3. Add a little water if you like.
4. Brush gently for 2–3 minutes, then rinse your mouth well.
5. For best results, use twice a day — morning and night.

FAQ

Q1: What is ODAIT® BeeRenew Advanced Gum Healing Toothpaste?
ODAIT® BeeRenew is a naturally formulated toothpaste that combines purified bee venom with clinically tested plant extracts to support gum repair and overall oral health. Use it just like a regular toothpaste — apply a small amount to your toothbrush and brush normally.

Q2: Can people with sensitive teeth use it?
Yes. ODAIT® BeeRenew is specially designed for sensitive teeth and gums. Its gentle, alcohol-free formula penetrates deep into exposed dentinal areas, helping to calm nerve sensitivity and prevent pain at the source. With continued use, it helps maintain lasting comfort for up to 24 hours.

Q3: Do I still need to use regular toothpaste afterwards?
No. ODAIT® BeeRenew is a complete oral care solution that cleans, protects, and nourishes your gums and teeth. However, if you prefer a toothpaste with added fluoride or a stronger mint flavor, you can use a small amount after brushing with BeeRenew.

Q4: Does it have any strong or chemical smell?
Not at all. ODAITe® BeeRenew is made with 100% natural ingredients and contains no alcohol or synthetic fragrances. It has a light, refreshing mint aroma and is completely free from harsh chemicals. Both the tube and cap are made from recyclable, eco-friendly materials.

Q5: Can I use it on mouth sores or ulcers? Will it sting?
No. The formula is gentle and non-irritating, unlike alcohol-based products that cause burning. The bee venom complex helps reduce inflammation, inhibit bacteria, and support the healing of gums and oral tissues — making it suitable even for sensitive areas.